A | 这种新的分子癌症治疗方法依赖于一种特定的分子，它可以寻找围绕癌细胞的酸性环境。 (ECNS) -- Artificial intelligence is reshaping cross-border e-commerce in east China's Zhejiang Province, enhancing product competitiveness, streamlining manufacturing and transforming marketing. Merach, a Zhejiang-based smart fitness brand, has developed an AI assistant that offers personalized training plans and automatically adjusts equipment resistance. Powered by intelligent motion algorithms and AR technology, its products have become top sellers on cross-border e-commerce platforms and are exported to over 50 countries and regions. AI is also helping original equipment manufacturers upgrade. Huang Qiangshuai, manager of Zhejiang Shuaishuai Technologies Co., Ltd., has established an AI system to prioritize production schedules across its contract manufacturing, design-and-manufacturing services and own-brand operations. "With the fluctuating delivery dates and diverse demands of cross-border e-commerce orders, AI serves as the optimal balancer," he said. Small businesses are using AI to lower marketing barriers. Hangzhou entrepreneur Tai Guyue applies AI tools for media outreach, planning and data analysis. "AI can turn some intermediate steps into one‑click solutions," she said. A survey by Amazon showed more than 98% of Chinese sellers use AI tools in store operations, with 16% deploying AI workflows or agents for automated multitasking. Zhejiang is also promoting AI courses at universities and developing provincial‑level cross‑border e‑commerce parks to sustain growth. Zhejiang is also promoting AI-related courses at universities and developing provincial-level cross-border e-commerce industrial parks to sustain the sector's growth. (By Tang Yuxian) 
。但是，为了使细胞有足够的酸性，它们不能是“冷”的肿瘤，这种肿瘤几乎没有免疫活性。
B | 这就是被称为STING激动剂的药物发挥作用的地方。这些药物使肿瘤“燃烧”起来，允许免疫系统对其作出反应。然而，找到"冷"癌细胞可能很困难。
C | 这就是新的分子癌症疗法发挥作用的地方。研究人员本月在《肿瘤学前沿》（Frontiers of Oncology）杂志上发表了一项关于该分子的研究。根据该研究，该分子被称为pH值低的插入肽（pHLIP），它被吸引到酸性环境。
D | 通过使用该分子引导药物到肿瘤和癌细胞，他们能够将它们踢出"寒冷"的肿瘤范围，推动免疫系统进行反击。然后，他们可以使用免疫检查点抑制剂来有效地移除使免疫系统不至于用力过猛的自然刹车。这种分子癌症治疗方法让免疫系统更长时间地对抗癌症。这是一个双重的系统，基本上允许研究人员准确地引导药物到它们需要的地方。近年来，我们已经看到越来越多像这种新的分子癌症治疗方法这样的靶向选择出现了。一种针对癌细胞的病毒也一直在进行，我们甚至看到研究人员在测试一种能杀死皮肤癌的凝胶。在测试分子癌症治疗方法时，研究人员将pHLIP与STING激动剂耦合在一起，然后对20只患有结肠直肠肿瘤的小鼠进行治疗。他们发现，在一次注射后，18只小鼠的肿瘤在几天内完全消失。在另一组有较大肿瘤的小鼠中，他们看到接受治疗的10只小鼠中有7只肿瘤消失了。
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